A Randomized Case-controlled Clinical Trial of the Effect of Preemptive Etoricoxib, Prednisolone and a Control Group on of Postoperative Sequelae after Surgical Removal of Impacted Mandibular Third Molars

Background: The aim of this study was to compare the anti-inflammatory effects prednisolone andetoricoxib after third molar extraction.Method: A prospective, controlled conducted on 39 volunteers were allocated in three differentgroups, receive either 120 mg etoricoxib or 10mg 30 minutes prior procedure, and alsoa group who didn’t any medication pre-operatively.Baseline measurements obtainedpreoperatively, subsequent assessments made immediate postoperative, at 48 hours 7 daysafter surgery measure postoperative facial swelling by use linear measurements, interincisal mouthopening width visual analog scale score for pain. amount analgesics consumed recorded.Descriptive statistics used two groups P < 0.05.Conclusion: Considering results that obtained upon efficacy different pre-emptive medication,Etoricoxib showed statistically significant values terms pain reduction restriction mouth opening,in other hand significance edema reduction.